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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC6
All Species:
16.67
Human Site:
S123
Identified Species:
28.21
UniProt:
Q99741
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99741
NP_001245.1
560
62720
S123
H
Q
N
K
I
L
S
S
V
R
K
S
Q
E
I
Chimpanzee
Pan troglodytes
XP_001170406
560
62717
S123
H
Q
N
K
I
L
S
S
V
R
K
S
Q
E
I
Rhesus Macaque
Macaca mulatta
XP_001096756
559
62520
S123
D
H
N
K
I
L
S
S
V
R
K
S
Q
E
I
Dog
Lupus familis
XP_537648
559
62507
V123
Q
N
K
T
H
S
S
V
R
K
D
Q
E
V
T
Cat
Felis silvestris
Mouse
Mus musculus
O89033
562
62595
S124
R
Q
H
Q
I
R
S
S
S
A
Q
R
S
P
E
Rat
Rattus norvegicus
NP_001101768
561
62295
S124
P
Q
H
Q
I
L
S
S
A
Q
R
G
Q
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519126
361
39672
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001081844
554
60731
R123
P
Y
Q
L
S
P
V
R
K
G
Q
E
T
P
P
Zebra Danio
Brachydanio rerio
NP_001120805
561
61262
R143
I
S
R
P
S
P
T
R
L
N
E
T
S
C
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648247
662
75116
P218
Q
K
Q
Q
E
K
P
P
T
K
Q
P
N
K
N
Honey Bee
Apis mellifera
XP_625142
549
62089
S132
D
K
L
N
L
I
S
S
P
D
K
E
E
K
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999666
582
64455
P126
L
S
S
P
T
K
S
P
S
K
R
P
E
S
F
Poplar Tree
Populus trichocarpa
XP_002299817
498
55546
A115
E
V
L
H
V
S
T
A
P
S
S
A
V
C
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P09119
513
58018
F126
D
M
I
I
R
Q
K
F
Q
S
L
P
L
S
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96
89.1
N.A.
79.5
80
N.A.
45.3
N.A.
63.7
49
N.A.
33.9
36
N.A.
40
Protein Similarity:
100
100
97.5
93.5
N.A.
87.3
88.9
N.A.
52.8
N.A.
77.5
67.3
N.A.
52.1
57.3
N.A.
58.5
P-Site Identity:
100
100
86.6
6.6
N.A.
26.6
46.6
N.A.
0
N.A.
0
0
N.A.
0
20
N.A.
6.6
P-Site Similarity:
100
100
86.6
20
N.A.
46.6
73.3
N.A.
0
N.A.
6.6
26.6
N.A.
33.3
60
N.A.
33.3
Percent
Protein Identity:
25.8
N.A.
N.A.
N.A.
20.1
N.A.
Protein Similarity:
46.4
N.A.
N.A.
N.A.
41.2
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
8
8
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% C
% Asp:
22
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% D
% Glu:
8
0
0
0
8
0
0
0
0
0
8
15
22
29
8
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% G
% His:
15
8
15
8
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
8
36
8
0
0
0
0
0
0
0
0
22
% I
% Lys:
0
15
8
22
0
15
8
0
8
22
29
0
0
15
0
% K
% Leu:
8
0
15
8
8
29
0
0
8
0
8
0
8
0
15
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
22
8
0
0
0
0
0
8
0
0
8
0
8
% N
% Pro:
15
0
0
15
0
15
8
15
15
0
0
22
0
15
8
% P
% Gln:
15
29
15
22
0
8
0
0
8
8
22
8
29
0
0
% Q
% Arg:
8
0
8
0
8
8
0
15
8
22
15
8
0
0
8
% R
% Ser:
0
15
8
0
15
15
58
43
15
15
8
22
15
15
8
% S
% Thr:
0
0
0
8
8
0
15
0
8
0
0
8
8
0
15
% T
% Val:
0
8
0
0
8
0
8
8
22
0
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _